However, the use of separate B6 supplements (apart from the RDA amounts in typical multivitamin preparations) is inconclusive and not recommended. Adequate blood levels of B6 may be associated with lower risk of cancers, compared to low blood levels. The vitamin in supplement form shows the most promise for the treatment of pregnancy-induced nausea, but such use should only occur under the supervision of a physician. Vitamin B6 has been widely studied for its role in disease prevention. Even higher amounts of vitamin B6 supplements are sometimes prescribed for medical reasons, but under the supervision of a physician as excess vitamin B6 can cause toxicity. This amount can only be achieved by taking supplements. The UL for adults 19 years and older is 100 mg daily, with slightly lesser amounts in children and teenagers. UL: A Tolerable Upper Intake Level (UL) is the maximum daily dose unlikely to cause adverse side effects in the general population. For pregnancy and lactation, the amount increases to 1.9 mg mcg and 2.0 mg, respectively.
The RDA for women ages 14-18 years is 1.2 mg 19-50 years, 1.3 mg and 51+ years, 1.5 mg. RDA: The Recommended Dietary Allowance (RDA) for men ages 14-50 years is 1.3 mg daily 51+ years, 1.7 mg.
PLP is a coenzyme that assists more than 100 enzymes to perform various functions, including the breakdown of proteins, carbohydrates, and fats maintaining normal levels of homocysteine (since high levels can cause heart problems) and supporting immune function and brain health. Pyridoxal 5’ phosphate (PLP) is the active coenzyme form and most common measure of B6 blood levels in the body. Vitamin B6, or pyridoxine, is a water-soluble vitamin found naturally in many foods, as well as added to foods and supplements.
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